General objective

To update knowledge about eosinophilic esophagitis, including its epidemiological, diagnostic and therapeutic aspects, with a multidisciplinary approach, and based on the most up-to-date scientific evidence and best clinical practice.

Specific objectives

1. To know the current epidemiological characteristics of eosinophilic esophagitis, including its incidence and prevalence and temporal trends, globally and in European environments. Defining the current risk factors identified for the development of the disease, and to understand the pathophysiological bases by which they interact with the mucosal-associated immune system to generate the disease.
2. To recognize the forms of clinical presentation of the disease throughout the different ages of life.
3. To know the role that endoscopy plays in the diagnostic process of eosinophilic esophagitis, and learn to identify the main endoscopic findings in these patients, as well as their accuracy in reaching the diagnosis of the disease.
4. To learn the most appropriate procedure for taking esophageal biopsies in eosinophilic esophagitis, including their number and location to obtain maximum diagnostic yield. To recognize the main histopathological findings associated with eosinophilic esophagitis.
5. To expose the associations described between eosinophilic esophagitis and different atopic manifestations. To define the role of food allergy testing in the diagnostic and therapeutic process of patients with eosinophilic esophagitis.
6. To define the current treatment goals for eosinophilic esophagitis, according to the evolving characteristics of the disease and its natural history.
7. To know the efficacy (in terms of its ability to improve symptoms and restore histology) and safety of proton pump inhibitor therapy in children and adults with eosinophilic esophagitis. To define the doses to be used to in the short- and long-term management of patients responding to this therapy.
8. To know the efficacy (in improving symptoms and restoring histology) and safety of swallowed topical steroid treatment in children and adults with eosinophilic oesophagitis. To present the short-term and long-term results of trials with these drugs. Discuss the differences between drugs, the doses to be used and the differences in their presentations according to patient profiles.
9. Knowing the different alternatives based on the use of diets for the treatment of children and adults with eosinophilic esophagitis. Present the different dietary approaches and their expected efficacy. Provide practical advice for the implementation of dietary treatment in clinical practice.
10. To provide updated knowledge on the efficacy and safety of endoscopy dilation in the treatment of patients with eosinophilic esophagitis, throughout different ages. To recognize the indications of the technique and discuss the advantages of the different dilation devices.
11. Present the treatment algorithm for eosinophilic esophagitis proposed in the new evidence-based guidelines for the comprehensive management of this disease, defining the choice of therapy according to specific patient profiles.
12. To present and discuss the different areas of uncertainty in the diagnosis and therapy of EoE, and to acknowledge potential areas for future research.

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